Rhubarb extract

Introduction of Rhubarb extract：

Rhubarb extract is derived from the dried roots and rhizomes of Rheum palmatum, Rheum tanguticum, or medicinal rhubarb. Rheum palmatum and Rheum tanguticum are called rhubarb, which are mainly produced in Qinghai, Gansu, Sichuan and other places. The medicinal rhubarb is called southern rhubarb, which is mainly produced in Sichuan, Hubei and other places. Rhubarb tastes bitter and cold, and belongs to the stomach, liver and large intestine meridian. The active ingredients are anthraquinone compounds, including rhein, emodin, chrysophanol, aloe-emodin, emodin methyl ether, etc.

Specification of Rhubarb extract

Benefits of Rhubarb extract:

1. Effects on the digestive system

(1) Laxative effect: The main action site of laxative is in the large intestine. The active ingredients of rhubarb diarrhea are anthracene glycosides, mainly sennosides. Sennoside is decomposed under the action of intestinal bacterial enzymes to produce rhein anthrone, which can stimulate the large intestine mucosa, increase intestinal peristalsis and cause diarrhea. In addition, it can also inhibit Na+, K+-ATPase on the intestinal cell membrane, hinder Na+ transport, increase the osmotic pressure in the intestine, retain a large amount of water, and promote intestinal peristalsis and diarrhea.

(2) Choleretic and liver protection: Rhubarb extract can promote bile secretion, increase the content of bilirubin and bile acid in bile, relieve bile duct sphincter spasm, enhance duodenum and bile duct dilation, dredge bile duct and microscopic The accumulation of bile in the bile ducts.

2. Effects on the blood system

(1) Hemostatic effect: The hemostatic effect of rhubarb extract is exact and quick. The active ingredients are α-catechin and gallic acid. The mechanism of action is to promote the adhesion and aggregation of platelets; increase the number of platelets and fibrinogen content; reduce the activity of antithrombin Ⅲ; constrict the blood vessels in the injured area.

(2) Blood lipid-lowering effect: Rhubarb extract can reduce the levels of total cholesterol, triacylglycerol, low-density lipoprotein, very low-density lipoprotein and lipid peroxide. Rhubarb was made into a granule, and it was taken continuously for 2 months. The lipid-lowering effect was better, and no adverse reactions were seen.

(3) Blood-activating effect: rhubarb extract has a blood-thinning effect, which may be through the plasma osmotic pressure effect, which promotes the transfer of extracellular fluid to the blood vessel, thereby diluting the blood, resulting in a decrease in blood cells, and a decrease in blood viscosity, thereby enhancing the chemical book. Microcirculation, to achieve the purpose of promoting blood circulation.

3. Anti-infection effect

Rhubarb extract has inhibitory effect on a variety of Gram-positive and negative bacteria in vitro, especially sensitive to paratyphoid bacillus and Shigella. It also has a certain killing effect on hepatitis B virus, various fungi, amoeba, and trichomonas vaginalis. The main antibacterial ingredients are rhein, emodin and aloe-emodin. The antibacterial mechanism is mainly to inhibit the oxidation and dehydrogenation of intermediates of bacterial sugar metabolism, inhibit the synthesis of proteins and nucleic acids; inhibit the bacterial biological oxidase system; induce interferon.

4. Antipyretic effect

In the acute stage of acute or infectious diseases, the application of rhubarb extract can reduce the temperature, and the temperature can be lowered safely, without adverse reactions such as profuse sweating or collapse. Its antipyretic mechanism is: inhibiting the synthesis of prostaglandin E in the body temperature center, reducing the content of cyclic glycoside nucleic acid, expanding peripheral blood vessels and increasing heat dissipation to achieve the purpose of cooling.

5. Immunomodulatory effect

Rhubarb extract has a two-way regulatory effect on immune function, with different degrees of immunosuppression, and has inhibitory or blocking effects on cellular immunity and humoral immunity. Long-term application can cause thymus, spleen, Atrophy of immune organs such as lymph nodes. In addition, rhubarb can increase the phagocytosis of peritoneal macrophages in mice, promote the production of interferon in the human body, and improve immunity, so as to achieve the purpose of eliminating viruses.

6. Other effects

More and more scholars at home and abroad have proved that the tannin contained in rhubarb has a good antioxidant effect. Rhubarb polysaccharide also has obvious inhibitory effect on tumors, and also has hypolipidemic, diuretic, anti-inflammatory, and antihypertensive effects. identify

The above information is for reference only